ACE2 Knock-Out Model
In humans, ACE2 protein is involved in SARS-CoV-2 cells entry and responsible for pathology of COVID 19 .
However, Mice are low-sensitive to SARS-CoV infection, but can be poorly inoculated by the virus.
So knockout of ACE2 genes in MICE through genome editing will give opportunity to study the viral sensitivity and generation of COVID 19 model .
Availability of mice model
Mice are available for distribution in India for academic research. Please contact us firstname.lastname@example.org